The kidney used in the latest NYU transplant was procured from a pig with a single genetic edit—the removal of a gene that produces a sugar known as alpha gal. This sugar appears on the surface of pig cells and seems to be responsible for rapid rejection in humans. The pig was engineered by Revivicor, … Read more
NEW YORK — Doctors have transplanted a pig kidney into a New Jersey woman who was near death, part of a dramatic pair of surgeries that also stabilized her failing heart. Lisa Pisano’s combination of heart and kidney failure left her too sick to qualify for a traditional transplant, and out of options. Then doctors … Read more
Other than rejection of the organ, one of the most common transplant complications is infection. Doctors have to strike a balance when prescribing immunosuppressive drugs: too low a dose can lead to rejection, while too much can make a patient vulnerable to infection. Immunosuppressants are powerful drugs that can cause a range of side effects, … Read more
In early experiments, Lagasse found that if he injected healthy liver cells into the lymph nodes of mice, the cells would flourish and form a second, smaller liver to take over the functions of the animal’s failing one. The new livers grew up to 70 percent of the size of a native liver. “What happened … Read more
NEW YORK — Doctors in Boston have transplanted a pig kidney into a 62-year-old patient, the latest experiment in the quest to use animal organs in humans. Massachusetts General Hospital said Thursday that it’s the first time a genetically modified pig kidney has been transplanted into a living person. Previously, pig kidneys have been temporarily … Read more
Slayman received his first kidney transplant in 2018 from a human donor. The donor kidney initially functioned well, but Slayman started to go into kidney failure after years of living with diabetes. Diabetes is the leading cause of kidney disease, which can eventually result in kidney failure. He had no choice but to go on … Read more
WASHINGTON — The maker of Robitussin cough syrup is recalling several lots of products containing honey due to contamination that could pose a serious risk to people with weakened immune systems. Haleon’s recall covers eight lots of Robitussin Honey CF Max Day Adult and Robitussin Honey CF Max Nighttime Adult, which were distributed to stores … Read more
Surgeons externally attached a pig liver to a brain-dead human body and watched it successfully filter blood, a step toward eventually trying the technique in patients with liver failure. The University of Pennsylvania announced the novel experiment Thursday, a different spin on animal-to-human organ transplants. In this case, the pig liver was used outside the … Read more
That has led researchers to genetically alter pigs in an attempt to make their organs a better match. The biotech company that bred the pig for the Penn study, eGenesis of Cambridge, Massaschetts, is aiming to do that with gene editing. Scientists at the company used Crispr to make a total of 69 genetic edits … Read more
LONDON — Roy Calne, a pioneer of organ transplantation who led Europe’s first liver transplant operation in 1968, has died aged 93. Calne’s family said he died late Saturday in Cambridge, England, where he was professor emeritus of surgery at Cambridge University. Born in 1930, Calne trained as a doctor at Guy’s Hospital in London … Read more
