Unlocking the potential of patient-derived organoids for personalized sarcoma treatment

Unlocking the potential of patient-derived organoids for personalized sarcoma treatment

Investigators at the UCLA Health Jonsson Comprehensive Cancer Center have developed the largest collection of sarcoma patient-derived organoids to date that can help improve the understanding of the disease and better identify therapies that are most likely to work for each individual patient. The approach, detailed in the journal Cell Stem Cell, uses patients’ own … Read more

Treating newly-diagnosed Crohn’s patients with advanced therapy leads to dramatic improvements in outcomes

Unlocking the potential of patient-derived organoids for personalized sarcoma treatment

A large-scale clinical trial of treatment strategies for Crohn’s disease has shown that offering early advanced therapy to all patients straight after diagnosis can drastically improve outcomes, including by reducing the number of people requiring urgent abdominal surgery for treatment of their disease by ten-fold. The PROFILE trial, led by researchers at the University of … Read more