Novel insights into fluorescent ‘dark states’ illuminate ways forward for improved imaging

Novel insights into fluorescent ‘dark states’ illuminate ways forward for improved imaging

Scientists at St. Jude Children’s Research Hospital today announced a way to improve molecular scale distance measurements using single-molecule fluorescence resonance energy transfer (smFRET). smFRET quantifies the excitation and emission properties of chemicals called fluorophores. When an excited electron in the fluorophore relaxes, it emits light after a delay, causing the molecule to glow (fluoresce). … Read more