A drug candidate (pink) found to bind to the pocket between the cancer-related protein CCNE1 (green) and its partner CDK2 (blue) using the new paralog-hopping approach. Credit: Scripps Research Some proteins in the human body are easy to block with a drug; they have an obvious spot in their structure where a drug can fit, … Read more
Credit: Pixabay/CC0 Public Domain Iyashikei is a Japanese genre that, according to Japanese studies scholar Paul Roquet, tells stories that are designed to comfort and heal weary readers by creating an aesthetic of calm. In order to achieve this, as Roquet articulates, these stories are presented as tales with little or no plot conflict. That … Read more
An SwRI-led team detected carbon dioxide and hydrogen peroxide spectral signatures on Pluto’s largest moon Charon using Webb telescope observations (white), which extend the wavelength coverage of previous New Horizons flyby measurements (pink). These findings offer clues about the formation and evolution of Charon, shown in the background as imaged by New Horizons. Credit: Silvia … Read more
This artist’s impression shows Barnard b, a sub-Earth-mass planet that was discovered orbiting Barnard’s star. Its signal was detected with the ESPRESSO instrument on ESO’s Very Large Telescope (VLT), and astronomers were able to confirm it with data from other instruments. An earlier promising detection in 2018 around the same star could not be confirmed … Read more
A spokesperson for Sibelco said: “As of September 26th, we have temporarily halted operations at the Spruce Pine facilities in response to these challenges. “We are working closely with our local team to safely restart operations as soon as we can and are actively coordinating with local authorities and other partners to manage the situation. … Read more
Recent models highlight regional climate impacts from the equator to the poles. Credit: Collins M et al/Frontiers The effects of climate change are not distant future scenarios or confined to remote parts of the world—they are unfolding now, right in our own backyards. In 2023, extreme weather events impacted communities across every inhabited continent, causing … Read more
Credit: Unsplash/CC0 Public Domain The first major study of social media behavior during wartime has found that posts celebrating national and cultural unity in a country under attack receive significantly more online engagement than derogatory posts about the aggressors. University of Cambridge psychologists analyzed a total of 1.6 million posts on Facebook and Twitter (now … Read more
Changes in Tropical cyclone (TC) cold wakes with respect to distance from coast within 500 km of the U.S. (a) Southeast coast (SEC) and (b) Gulf coast during the period 1982–1999 (blue), 2000–2020 (yellow). Nearshore Atlantic hurricane track locations within 200 km of the U.S. (c) SEC and (e) Gulf coast. Blue dots represent the period 1982–1999 and yellow dots represent … Read more
This NASA/ESA Hubble Space Telescope image features the spiral galaxy IC 1954. Credit: ESA/Hubble & NASA, D. Thilker, J. Lee and the PHANGS-HST Team This image from the NASA/ESA Hubble Space Telescope features the spiral galaxy IC 1954, located 45 million light-years from Earth in the constellation Horologium. It sports a glowing bar in its … Read more
Credit: Pixabay/CC0 Public Domain Undecided voters are less likely to cast their ballot, according to a new study which shows how the fragmentation of the political party system in the UK is fueling low turnout at elections. The number of citizens undecided in how they’d vote has risen in Western democracies. People are becoming less … Read more
