Fever drives enhanced activity, mitochondrial damage in immune cells

Fever drives enhanced activity, mitochondrial damage in immune cells

Fever temperatures rev up immune cell metabolism, proliferation and activity, but they also — in a particular subset of T cells — cause mitochondrial stress, DNA damage and cell death, Vanderbilt University Medical Center researchers have discovered. The findings, published Sept. 20 in the journal Science Immunology, offer a mechanistic understanding for how cells respond … Read more