Pan-cancer analysis uncovers a new class of promising CAR T–cell immunotherapy targets

Pan-cancer analysis uncovers a new class of promising CAR T–cell immunotherapy targets

Targeting anti-cancer therapy to affect cancer cells but not healthy cells is challenging. For chimeric antigen receptor (CAR) T-cell immunotherapy, where a patient’s own immune cells are re-engineered to attack cancer cells, many solid and brain cancers lack an effective target. St. Jude Children’s Research Hospital scientists have identified 156 potential targets through a comprehensive … Read more