“This is a terrible disease,” says Samarth Kulkarni, president and CEO of Crispr Therapeutics. “Every day feels like a big burden. Patients have this constant specter of mortality hanging over them.” The culprit is abnormal hemoglobin, the protein that carries oxygen through the body. The problem arises from a mutation in the HBB gene. Everyone … Read more
Researchers at the company collected the patient’s B cells using a machine that removes blood, separates out a particular component, then returns the rest to circulation. There are billions of B cells in the body; Immusoft uses only a portion. “The body is constantly regenerating and producing new B cells,” Ainsworth says. To get the … Read more
So far, only nine centers across the US are currently offering Casgevy, which may limit who gets access to it. Vertex says the number of participating sites will grow in the coming weeks and months. And despite the promise of a pain-free future, the grueling process of getting Casgevy may be a deterrent for some. … Read more
