The health impacts of a complex protein that plays a major role in the development of Alzheimer’s disease and heart conditions can be lessened by three kinds of drug inhibitors, according to scientists at the University of Colorado Anschutz Medical Campus. In an overview of the protein and the inhibitors published today in the journal … Read more
Galantamine is a common medication used by people with Alzheimer’s disease and other forms of dementia around the world to treat their symptoms. Unfortunately, synthesizing the active compounds in a lab at the scale needed isn’t commercially viable. The active ingredient is extracted from daffodils through a time-consuming process, and unpredictable factors, such as weather … Read more
U.S. veterans of the wars in Afghanistan and Iraq who suffered mild traumatic brain injury from exposure to explosive blasts were found to have changes in cerebrospinal fluid proteins that are typically seen in people who develop Alzheimer’s disease, according to researchers at the University of Washington School of Medicine and VA Puget Sound Health … Read more
Monitoring daily activity patterns using a wrist-worn device may detect early warning signs of Alzheimer’s disease, according to a new study led by researchers at the Johns Hopkins Bloomberg School of Public Health. The researchers analyzed movement data from wristwatch-like devices called actigraphs worn by 82 cognitively healthy older adults who were participants in a … Read more
New research published today suggests there is a link between abnormal blood levels of amyloid — a protein associated with Alzheimer’s disease — and subtle changes in brain microstructures on a type of MRI, findings that could lead to a new way to detect Alzheimer’s earlier in people with no clinical signs. Researchers analyzed the … Read more
People at risk of Alzheimer’s disease have impaired spatial navigation prior to problems with other cognitive functions, including memory, finds a new study led by UCL researchers. The research, published in Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association, used virtual reality to test the spatial navigation of 100 asymptomatic midlife adults, aged 43-66, … Read more
UC San Francisco scientists have found a way to predict Alzheimer’s Disease up to seven years before symptoms appear by analyzing patient records with machine learning. The conditions that most influenced prediction of Alzheimer’s were high cholesterol and, for women, the bone-weakening disease osteoporosis. The work demonstrates the promise of using artificial intelligence (AI) to … Read more
People with higher exposure to traffic-related air pollution were more likely to have high amounts of amyloid plaques in their brains associated with Alzheimer’s disease after death, according to a study published in the February 21, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology. Researchers looked at fine particulate … Read more
UNC School of Medicine researcher Sarah Cohen, PhD, and Ian Windham, a former PhD student from the Cohen lab, have made a new discovery about apolipoprotein E (APOE) — the biggest genetic risk factor for late-onset Alzheimer’s disease. Older people who inherited a genetic variant called APOE4 from their parents have a two- or three-times … Read more
Immigrants living with dementia were more likely to present with agitation and aggression compared with their non-immigrant counterparts, a new study by Edith Cowan University (ECU) in collaboration with The Dementia Centre, HammondCare, found. Researchers from ECU’s Centre for Research in Aged Care and HammondCare’s The Dementia Centre noted that behaviours and psychological symptoms of … Read more
