Some diabetes drugs tied to lower risk of dementia, Parkinson’s disease

Some diabetes drugs tied to lower risk of dementia, Parkinson’s disease

A class of drugs for diabetes may be associated with a lower risk of dementia and Parkinson’s disease, according to a study published in the September 18, 2024, online issue of Neurology®, the medical journal of the American Academy of Neurology. The study looked at sodium-glucose cotransporter-2 (SGLT2) inhibitors, which are also known as gliflozins. … Read more

Genetic risk-factor overlap between Alzheimer’s disease, and all-cause and vascular dementias

Some diabetes drugs tied to lower risk of dementia, Parkinson’s disease

In landmark research, scientists at The University of Texas Health Science Center at San Antonio (UT Health San Antonio) have reported the largest-ever genome-wide association study of dementia from all causes, revealing an overlap of genetic risks including neurodegeneration, vascular factors and cerebral small-vessel disease. Genome-wide association studies help scientists identify genes associated with a … Read more

Light pollution a new Alzheimer’s risk factor

Some diabetes drugs tied to lower risk of dementia, Parkinson’s disease

Outdoor light at night could be a significant risk factor in Alzheimer’s disease, according to new research from Rush. While light pollution is associated with increased risk of some disorders and diseases, this is the first time it had been associated with Alzheimer’s disease. The study was conducted at Rush University System for Health and … Read more

Falling for financial scams? It may signal early Alzheimer’s disease

Some diabetes drugs tied to lower risk of dementia, Parkinson’s disease

Older adults who are more vulnerable to financial scams may have brain changes linked to a higher risk of Alzheimer’s disease, according to a first-of-its-kind study led by researchers at the USC Dornsife College of Letters, Arts and Sciences. Nearly 7 million Americans are living with Alzheimer’s disease, the fifth leading cause of death among … Read more

New research on anesthesia unlocks important clues about the nature of consciousness

Some diabetes drugs tied to lower risk of dementia, Parkinson’s disease

For decades, one of the most fundamental and vexing questions in neuroscience has been: what is the physical basis of consciousness in the brain? Most researchers favor classical models, based on classical physics, while a minority have argued that consciousness must be quantum in nature, and that its brain basis is a collective quantum vibration … Read more

Alzheimer’s drug may slow down cognitive decline in dementia with Lewy bodies

Some diabetes drugs tied to lower risk of dementia, Parkinson’s disease

Dementia with Lewy bodies is a type of dementia that is similar to both Alzheimer’s disease and Parkinson’s disease but studies on long-term treatments are lacking. A new study from Karolinska Institutet in Sweden, published in Alzheimer’s & Dementia: The Journal of the Alzheimer’s Association, highlights the potential cognitive benefits of cholinesterase inhibitor treatment. Lewy … Read more

Multiple sclerosis appears to protect against Alzheimer’s disease

Some diabetes drugs tied to lower risk of dementia, Parkinson’s disease

People with multiple sclerosis (MS) are far less likely than those without the condition to have the molecular hallmarks of Alzheimer’s disease, according to new research from Washington University School of Medicine in St. Louis. The discovery suggests a new avenue of research through which to seek Alzheimer’s treatments, said Matthew Brier, MD PhD, an … Read more

Cancer drug could treat early-stage Alzheimer’s disease, study shows

Some diabetes drugs tied to lower risk of dementia, Parkinson’s disease

A type of drug developed for treating cancer holds promise as a new treatment for neurodegenerative diseases such as Alzheimer’s, according to a recent study by researchers at Penn State, Stanford University and an international team of collaborators. The researchers discovered that by blocking a specific enzyme called indoleamine-2,3-dioxygenase 1, or IDO1 for short, they … Read more

Novel sequencing approaches highlight role of brain gene activity in Alzheimer’s disease

Some diabetes drugs tied to lower risk of dementia, Parkinson’s disease

Innovative new research has revealed that the activity of different versions of genes expressed in the brain is associated with the accumulation of the protein tau, which is a hallmark of Alzheimer’s disease. The University of Exeter Medical School research used new ‘long-read’ sequencing technology to progress understanding of how genes are expressed in the … Read more