Wegovy Can Keep Weight Off for at Least 4 Years, Research Shows

Wegovy Can Keep Weight Off for at Least 4 Years, Research Shows

A large, long-term trial of the weight-loss medication Wegovy (semaglutide) found that people tended to lose weight over the first 65 weeks on the drug—about one year and three months—but then hit a plateau or “set point.” But that early weight loss was generally maintained for up to four years while people continued taking the … Read more

Tiger beetles fight off bat attacks with ultrasonic mimicry

Tiger beetles fight off bat attacks with ultrasonic mimicry

Bats, as the main predator of night-flying insects, create a selective pressure that has led many of their prey to evolve an early warning system of sorts: ears uniquely tuned to high-frequency bat echolocation. To date, scientists have found at least six orders of insects — including moths, beetles, crickets and grasshoppers — that have … Read more

Hawaii study shows almost 75% of Maui wildfire survey participants have respiratory issues

Hawaii study shows almost 75% of Maui wildfire survey participants have respiratory issues

A man views the aftermath of a wildfire in Lahaina, Hawaii, Aug. 19, 2023. A University of Hawaii study examining the health effects of last year’s deadly wildfires on Maui found that up to 74% of participants may have difficulty breathing and otherwise have poor respiratory health, and almost half showed signs of compromised lung … Read more

Heating proteins to body temperature reveals new drug targets

Tiger beetles fight off bat attacks with ultrasonic mimicry

Some proteins shift their shape when exposed to different temperatures, revealing previously unknown binding sites for medications. The findings, published today in Nature, could revolutionize wide swathes of biology by fundamentally changing how protein structure is studied and leveraged for drug design. The study was led by Van Andel Institute’s Juan Du, Ph.D., and Wei … Read more

Wildfire closes in on Canadian oil sands city

Wildfire closes in on Canadian oil sands city

Fort McMurray in Canada’s Alberta province was partially evacuated as a growing wildfire neared the city. A wildfire in Canada’s major oil-producing region doubled in size as it drew closer to the city of Fort McMurray on Wednesday, but officials were hopeful shifting winds could soon push it away. The blaze scorched almost 21,000 hectares … Read more

This time, it’s personal: Enhancing patient response to cancer immunotherapy

Tiger beetles fight off bat attacks with ultrasonic mimicry

Immunotherapy has revolutionized the way we treat cancer in recent years. Instead of targeting the tumor itself, immunotherapies work by directing patients’ immune systems to attack their tumors more effectively. This has been especially impactful in improving outcomes for certain difficult-to-treat cancers. Still, fewer than half of all cancer patients respond to current immunotherapies, creating … Read more