Cognitive deficits from meth and PCP use are generated by a common neurotransmitter switch

Cognitive deficits from meth and PCP use are generated by a common neurotransmitter switch

The effects of sustained drug abuse can manifest in many ways. Loss of memory and reduced cognitive functions are some of the effects that can persist for years. Neurobiologists at the University of California San Diego have now identified a mechanism in the brain that generates drug-induced cognitive impairments. Scientists in the Department of Neurobiology, … Read more

Breathing may introduce microplastics to the brain—new study

Breathing may introduce microplastics to the brain—new study

Credit: Unsplash/CC0 Public Domain Small plastic particles are everywhere: in the soil where our food is grown, in the water we drink and in the air we breathe. They got there from the plastic we throw away, which ends up in landfill sites, rivers and seas. There the plastic waste slowly breaks down, releasing tiny … Read more

Beetroot shots to baking powder: the science behind sport’s most popular supplements | Nutrition

Beetroot shots to baking powder: the science behind sport’s most popular supplements | Nutrition

In August, Keely Hodgkinson won Great Britain’s only Olympic gold medal on the track. The foundation of the 800m star’s world-beating performance came from a regime that comprises intensity over mileage, cross-training, sand-dune workouts and a £15 supplement that has been around for years but has enjoyed a breakthrough year in 2024. Hodgkinson uses sodium … Read more

An International Space Station Leak Is Getting Worse—and Keeping NASA Up at Night

An International Space Station Leak Is Getting Worse—and Keeping NASA Up at Night

US space officials do not like to talk about the perils of flying astronauts on the aging International Space Station, elements of which are now more than a quarter of a century old. However, a new report confirms that NASA managers responsible for operating the space station are seriously concerned about a small Russian part … Read more

Wolves vs Liverpool LIVE: Team news and line-ups as Alisson fit to start for Reds

Wolves vs Liverpool LIVE: Team news and line-ups as Alisson fit to start for Reds

(Getty Images) Sign up to Miguel Delaney’s Reading the Game newsletter sent straight to your inbox for free Sign up to Miguel’s Delaney’s free weekly newsletter Sign up to Miguel’s Delaney’s free weekly newsletter Liverpool face Wolves in today’s late kick-off at the Molineux, with Arne Slot’s side looking to retain a place near the … Read more

Metabolic reprogramming of T cells may enhance checkpoint inhibitor therapy

Cognitive deficits from meth and PCP use are generated by a common neurotransmitter switch

Stimulating a key metabolic pathway in T cells can make them work more effectively against tumors when combined with immune checkpoint inhibitor therapy, according to a preclinical study led by researchers at Weill Cornell Medicine. The findings suggest a potential strategy for enhancing the potency of anticancer immunotherapies. In the study, which appears Sept. 26 … Read more

Bears have learned to open doors in California town

Bears have learned to open doors in California town

Credit: Unsplash/CC0 Public Domain Owning a home in Southern California isn’t just a dream for humans. Apparently, the bears want in on the market too. Just ask residents and city officials in Sierra Madre, who in the last few years have seen their furry, four-legged neighbors amble out of the forest and barge into their … Read more

A Lawsuit From Backers of a ‘Startup City’ Could Bankrupt Honduras

A Lawsuit From Backers of a ‘Startup City’ Could Bankrupt Honduras

The flurry of private contracts became part of a “kleptocratic” regime, according to one 2017 report by the Carnegie Endowment for International Peace. Nearly all of the ISDS claims have their roots in contracts, laws or other agreements made during this period. For the farmers and villagers being pushed off their land, or having their … Read more

Newcastle v Manchester City LIVE: Premier League result and reaction after Anthony Gordon penalty earns Magpies point

Newcastle v Manchester City LIVE: Premier League result and reaction after Anthony Gordon penalty earns Magpies point

(AFP via Getty Images) Manchester City were dealt another early blow to their Premier League title hopes as Newcastle secured an impressive home point at St James’ Park. In the absence of influential midfielder Rodri, out for the season after suffering a serious knee injury against Arsenal, Pep Guardiola’s side lacked their usual calm, composure … Read more